Amaryllidaceae alkaloids inhibit nuclear-to-cytoplasmic export of ribonucleoprotein (RNP) complex of highly pathogenic avian influenza virus H5N1
نویسندگان
چکیده
منابع مشابه
Amaryllidaceae alkaloids inhibit nuclear‐to‐cytoplasmic export of ribonucleoprotein (RNP) complex of highly pathogenic avian influenza virus H5N1
BACKGROUND Few drugs are currently licensed to treat influenza A infection, and new therapies are needed, especially for highly pathogenic strains. Traditional medicinal plants, such as Lycoris radiata, are a potential source of new antiviral agents. OBJECTIVE To test 15 Amaryllidaceae alkaloids isolated from the bulbs of L. radiata in vitro for antiviral activities against influenza virus ty...
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Author affiliations: Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany (I.A. Asante, S. Bertram, G. Gabriel); Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana (I.A. Asante, W.K. Ampofo); Center for Structural and Cellular Biology in Medicine at the University of Lübeck, Lübeck, Germany (S. Bertram, G. Gabriel); Veterinary S...
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ژورنال
عنوان ژورنال: Influenza and Other Respiratory Viruses
سال: 2012
ISSN: 1750-2640
DOI: 10.1111/irv.12035